HYPP RESULTS
Hyperkalemic Periodic Paralysis (HYPP)
Choose your horse’s result for more information.
N/N Results
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What do these results mean for my horse?
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N/N Results
Your horse did not inherit a copy of HYPP and is considered normal. They cannot pass on the mutation to offspring themselves.
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What are symptoms of a HYPP episode?
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HYPP affected horses can experience a number of symptoms. Episodes can last anywhere from minutes to hours. Horses severely affected by HYPP can be dangerous to handle due to the risk of sporadic muscle spasms and potential collapse or paralysis. Common symptoms include:
- Sporadic muscle spasms.
- Loud breathing.
- Weakness.
- Collapse.
- Paralysis.
The signs of HYPP are often confused with other conditions such as "tying-up", colic, seizures and choking. During an attack, horses with HYPP are conscious and aware of their surroundings.
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-
What causes a HYPP episode?
-
Factors that may trigger an episode:
- Stress.
- High potassium diet.
- Rapid changes in feed.
- Fasting followed by a high potassium meal such as alfalfa.
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-
How is HYPP managed?
-
Optimally, HYPP can be managed most effectively with responsible breeding. Taking care to decrease the risk of passing on the mutation to offspring is the best-case scenario.
For horses that are affected, HYPP can be managed well through diet and exercise. Coordinating a management plan with a veterinarian with working knowledge of the disease is extremely important, as each individual horse has varying management needs.
Diets should consist of less than 5% potassium, avoiding high potassium feeds such as alfalfa, brome hay, soybean meal, sugar molasses, and beet molasses. Alternatively, recommended feeds are oats, corn, wheat, barley, and later cuts of timothy or Bermuda grass. Supplementing your horse with vitamin E, selenium, salt, and balanced minerals where indicated can be helpful. Avoid long periods of fasting if possible, feeding small, frequent meals instead. Additionally, allowing frequent turnout and/or exercising regularly is recommended for managing the disease.
Exercise should be done with safety in mind not only for your horse, but yourself as well. Light exercise may be slowly increased to more demanding exercise.
Be sure to inform your vet of your horse's HYPP status prior to general anesthesia. While horses affected by HYPP can be sedated, the veterinarian should be prepared to administer intravenous calcium in fluids if necessary to treat an episode.
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-
How do I treat a HYPP episode?
-
If your horse experiences a mild HYPP attack (exhibits muscle tremors but remains standing), contact your veterinarian. You can exercise your horse by walking or longeing, using caution as the horse could stumble or fall.
If your horse experiences a severe attack (extreme muscle tremors and/or collapse), emergency medical treatment is necessary. Contact your veterinarian immediately.
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What does this mean for breeding?
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When breeding any horse, probability of offspring inheriting genetic mutations should always be a factor to consider.
Expected breeding outcomes are shown below. A normal HYPP gene is indicated by "N". A mutated HYPP gene is indicated by "H".
100% chance of a foal who does not carry a copy and is considered normal. They cannot pass on the mutation to offspring themselves.
50% chance of a foal who does not carry a copy and is considered normal. They cannot pass on the mutation to offspring themselves.
50% Chance of a foal who inherits one copy and likely to experience mild/moderate symptoms with severe symptoms possible. This horse can pass on HYPP to offspring
100% chance of a foal who inherits one copy and likely to experience mild/moderate symptoms with severe symptoms possible.
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Learn More
N/H Results
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What do these results mean for my horse?
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N/H Results
Your horse inherited one copy (heterozygous) of the HYPP mutation. HYPP is a dominant mutation. This means that a horse only needs ONE copy of the mutation to be affected by it. Since your horse only has one copy, they are likely to have less severe symptoms than a horse that has two copies. Though, this can depend heavily on the management of your horse. More severe symptoms are possible when not managed properly. The prognosis for affected horses (N/H) is good, although recurrent bouts of the disorder may occur. Ensuring proper management of your horse is the best way to aid in long-term maintenance.
-
-
What are symptoms of a HYPP episode?
-
HYPP affected horses can experience a number of symptoms. Episodes can last anywhere from minutes to hours. Horses severely affected by HYPP can be dangerous to handle due to the risk of sporadic muscle spasms and potential collapse or paralysis. Common symptoms include:
- Sporadic muscle spasms.
- Loud breathing.
- Weakness.
- Collapse.
- Paralysis.
The signs of HYPP are often confused with other conditions such as "tying-up", colic, seizures and choking. During an attack, horses with HYPP are conscious and aware of their surroundings.
-
-
What causes a HYPP episode?
-
Factors that may trigger an episode:
- Stress.
- High potassium diet.
- Rapid changes in feed.
- Fasting followed by a high potassium meal such as alfalfa.
-
-
How is HYPP managed?
-
Optimally, HYPP can be managed most effectively with responsible breeding. Taking care to decrease the risk of passing on the mutation to offspring is the best-case scenario.
For horses that are affected, HYPP can be managed well through diet and exercise. Coordinating a management plan with a veterinarian with working knowledge of the disease is extremely important, as each individual horse has varying management needs.
Diets should consist of less than 5% potassium, avoiding high potassium feeds such as alfalfa, brome hay, soybean meal, sugar molasses, and beet molasses. Alternatively, recommended feeds are oats, corn, wheat, barley, and later cuts of timothy or Bermuda grass. Supplementing your horse with vitamin E, selenium, salt, and balanced minerals where indicated can be helpful. Avoid long periods of fasting if possible, feeding small, frequent meals instead. Additionally, allowing frequent turnout and/or exercising regularly is recommended for managing the disease.
Exercise should be done with safety in mind not only for your horse, but yourself as well. Light exercise may be slowly increased to more demanding exercise.
Be sure to inform your vet of your horse's HYPP status prior to general anesthesia. While horses affected by HYPP can be sedated, the veterinarian should be prepared to administer intravenous calcium in fluids if necessary to treat an episode.
-
-
How do I treat a HYPP episode?
-
If your horse experiences a mild HYPP attack (exhibits muscle tremors but remains standing), contact your veterinarian. You can exercise your horse by walking or longeing, using caution as the horse could stumble or fall.
If your horse experiences a severe attack (extreme muscle tremors and/or collapse), emergency medical treatment is necessary. Contact your veterinarian immediately.
-
-
What does this mean for breeding?
-
When breeding any horse, probability of offspring inheriting genetic mutations should always be a factor to consider.
Expected breeding outcomes are shown below. A normal HYPP gene is indicated by "N". A mutated HYPP gene is indicated by "H".
50% chance of a foal who does not carry a copy and is considered normal. They cannot pass on the mutation to offspring themselves.
50% chance of a foal who inherits one copy and likely to experience mild/moderate symptoms with severe symptoms possible. This horse can pass on HYPP to offspring.
25% chance of a foal who does not carry a copy and is considered normal. They cannot pass on the mutation to offspring themselves.
50% chance of a foal who inherits one copy and likely to experience mild/moderate symptoms with severe symptoms possible. This horse can pass on HYPP to offspring.
25% chance of a foal who is homozygous(H/H) and more likely to experience severe symptoms. This horse will pass on HYPP to offspring 100% of the time.
50% chance of a foal who inherits one copy and likely to experience mild/moderate symptoms with severe symptoms possible. This horse can pass on HYPP to offspring.
50% chance of a foal who is homozygous(H/H) and more likely to experience severe symptoms. This horse will pass on HYPP to offspring 100% of the time.
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Learn More
H/H Results
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What do these results mean for my horse?
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H/H Results
Your horse inherited two copies (homozygous) of the HYPP mutation. Because your horse has two copies, they are more likely to experience severe symptoms. These horses should not be handled by beginners or youth, as sporadic muscle cramping and collapse are more likely. Proper management of your horse is vital to reducing symptoms. A horse that is managed well may still go on to have a successful performance career. The prognosis for homozygous horses (H/H) is good when horses are properly managed. Ensuring proper management of your horse is the best way to aid in long-term maintenance. Homozygous (H/H) horses are ineligible for registration with AQHA.
-
-
What are symptoms of a HYPP episode?
-
HYPP affected horses can experience a number of symptoms. Episodes can last anywhere from minutes to hours. Horses severely affected by HYPP can be dangerous to handle due to the risk of sporadic muscle spasms and potential collapse or paralysis. Common symptoms include:
- Sporadic muscle spasms.
- Loud breathing.
- Weakness.
- Collapse.
- Paralysis.
The signs of HYPP are often confused with other conditions such as "tying-up", colic, seizures and choking. During an attack, horses with HYPP are conscious and aware of their surroundings.
-
-
What causes a HYPP episode?
-
Factors that may trigger an episode:
- Stress.
- High potassium diet.
- Rapid changes in feed.
- Fasting followed by a high potassium meal such as alfalfa.
-
-
How is HYPP managed?
-
Optimally, HYPP can be managed most effectively with responsible breeding. Taking care to decrease the risk of passing on the mutation to offspring is the best-case scenario.
For horses that are affected, HYPP can be managed well through diet and exercise. Coordinating a management plan with a veterinarian with working knowledge of the disease is extremely important, as each individual horse has varying management needs.
Diets should consist of less than 5% potassium, avoiding high potassium feeds such as alfalfa, brome hay, soybean meal, sugar molasses, and beet molasses. Alternatively, recommended feeds are oats, corn, wheat, barley, and later cuts of timothy or Bermuda grass. Supplementing your horse with vitamin E, selenium, salt, and balanced minerals where indicated can be helpful. Avoid long periods of fasting if possible, feeding small, frequent meals instead. Additionally, allowing frequent turnout and/or exercising regularly is recommended for managing the disease.
Exercise should be done with safety in mind not only for your horse, but yourself as well. Light exercise may be slowly increased to more demanding exercise.
Be sure to inform your vet of your horse's HYPP status prior to general anesthesia. While horses affected by HYPP can be sedated, the veterinarian should be prepared to administer intravenous calcium in fluids if necessary to treat an episode.
-
-
How do I treat a HYPP episode?
-
If your horse experiences a mild HYPP attack (exhibits muscle tremors but remains standing), contact your veterinarian. You can exercise your horse by walking or longeing, using caution as the horse could stumble or fall.
If your horse experiences a severe attack (extreme muscle tremors and/or collapse), emergency medical treatment is necessary. Contact your veterinarian immediately.
-
-
What does this mean for breeding?
-
When breeding any horse, probability of offspring inheriting genetic mutations should always be a factor to consider.
Expected breeding outcomes are shown below. A normal HYPP gene is indicated by "N". A mutated HYPP gene is indicated by "H".
100% chance of a foal who inherits one copy and likely to experience mild/moderate symptoms with severe symptoms possible.
50% chance of a foal who inherits one copy and likely to experience mild/moderate symptoms with severe symptoms possible. This horse can pass on HYPP to offspring.
50% chance of a foal who is homozygous(H/H) and more likely to experience severe symptoms. This horse will pass on HYPP to offspring 100% of the time.
100% chance of a foal who is homozygous(H/H) and more likely to experience severe symptoms. This horse will pass on HYPP to offspring 100% of the time.
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-
Learn More